virtualbox.org

I just upgraded to a newer machine, and copied my vbox files over.

New host is as old host, Fedora 25. Guest is Windows 10.

A few moments after starting the guest, the entire host hangs and I have to manually reboot.

What can I do?

The new machine is Inspiron Desktop 3668.

Here's the dell hardware config:

1 998-CGTP Fixed Hardware Configuration $0.00
1 525-0033 McAfee LiveSafe Consumer 12 Month Subscription $39.91
1 332-1286 Non-Canada Orders $0.00
2 332-1530 Dell.com Order $0.00
1 CD-ID12623 $0.00
1 CID12623 $0.00
1 450-AAGO US Power Cord $0.00
1 658-BCCO McAfee 30day Trial $0.00
1 658-BCSB Microsoft(R) Office 30 Days Trial $0.00
1 817-BBBP None Required $0.00
1 658-BBTV Cyberlink Media Suite Essentials for Windows 10 and DVD drive (without Media) $0.00
1 640-BBPK Ship Information $0.00
1 340-APVH Packaging Inspiron 3650/55 $0.00
1 321-BCLZ Chassis with NPFC $0.00
1 658-BCUN Additional Software $0.00
1 389-BDBY No Label $0.00
1 480-AAJX Display Not Included $0.00
1 340-AGIK Safety/Environment and Regulatory Guide (English/French Multi-language) $0.00
1 340-BJTE Dell Dual Band Wireless 1707 Driver $0.00
2 340-ACQQ No Option Included $0.00
1 340-BKBL Placemat W10 $0.00
1 340-AFOG Onboard Audio Royalty Information $0.00
1 520-AABF External Speaker Not Included $0.00
1 275-BBBW Dell MS116 Wired Mouse, Black $0.00
1 580-ADJC Dell KB216 Wired Multi-Media Keyboard English Black $0.00
1 555-BDIY Dell Wireless 1707 Card (802.11BGN + Bluetooth 4.0, 2.4 GHz) $0.00
1 510-BBCC HD Audio with Waves MaxxAudio $0.00
1 429-AAYS DVDRW Optical Drive $0.00
1 389-BLST Intel(R) Core(TM) i7 Label $0.00
1 389-BUCL Regulatory label Inspiron 3668 $0.00
1 490-BDIV NVIDIA® GeForce® GTX 750Ti with 2GB DDR5 graphics memory $0.00
1 400-APEB 128GB SSD+1TB GB 7.2k HDD $0.00
1 370-ADJN 16GB DDR4 at 2400MHz $0.00
1 619-AHCY Windows 10 Home-HE (64bit) English $0.00
1 338-BKZG 7th Generation Intel(R) Core(TM) i7-7700 processor (8MB Cache, up to 4.20 GHz) $0.00
1 801-1732 Mail In Service after Remote Diagnosis, 1 Year $0.00
1 801-1699 Dell Limited Hardware Warranty Initial Year $0.00

The information you provided, while perhaps great if I was a Dell service engineer, is not very useful for diagnosing a VM problem. What we need is the VM log. With the VM fully shut down, right click it in GUI. Select "Show Log" and save "VBox.log" (ONLY) to a zip file. Attach the zip here.

Sorry, here you go.

Try disabling secure boot in the host bios.

I did. I wasn't able to even boot until I did that.

I also see a lot of OpenGL issues. You might try to install the nVidia drivers instead of the open source ( nouveau ) drivers on the host.