Hi folks.
I'm running Debian Jessie Gnome hosted on a mid-2010 iMac with Sierra and on a new-ish MSI laptop running Windows 8. When 3D acceleration is selected, some applications leave a ghost on the desktop when they exit that prevents any mouse clicks until you bring up the activities screen using the keyboard shortcut (alt-F1). Some application windows aren't present in the tiled display, but some are and have to be killed using the "X" icon. Also, when switching to and from full screen mode, the whole guest display flashes orange or yellow. This happens on both hosts, but more often on the iMac.
A previous thread on this (from January 2016) seems to indicate that it is a hardware driver issue, but that seems unlikely since it is happening on both the iMac, which uses Radeon hardware, and the MSI, which has a GeForce card.
I am running Virtualbox version 5.1.14 r112924. The guest additions are installed on both hosts.
Please let me know if I can provide any more information. Thank you in advance for any help with this.