I installed Virtualbox 4.2.18-88780 on a Mac Mini running MacOS X 10.8.4. There is a Ubuntu 12.04 Server as guest.
I can enter the webapplication that is hosted on this guest. After a while it is not possible to access the app anymore. I have to login to the Mac via VNC, click in the guest window and strike a key. And only then I can access the webapp again. It seems that the virtual network interface (bridge mode) enters some kind of sleep mode