virtualbox.org

This (Dell laptop) is running 64bit Windows 7 home premium.
1. Is it possible to load vbox 4.1.16 and then instal MSDOS 6.x?
2. Please, any pointers to getting started?

Main purpose is to run various old calculation programs - all character based producing lists of significant (if boring) numbers, no exotic graphics.

TIA

Sure is. You might want to look through Other guests for pointers and issues

Main thing to remember is not to make things too big. It's DOS.