Yeah, that's about it. I use iTunes, occasionally Flash, and I test web development in IE 6 and 7 (have to support the poor fools who don't know any better).
In VirtualBox, my iPod is generally recognized - I get the disconnect hardware icon and all, but it hoses iTunes. I've tried plugging in before launching iTunes, as well as once the program is running - it doesn't seem to make any difference.
I guess if DRM goes away completely, Apple might stop trying to prevent the open source community from replicating their software, but that doesn't seem to be happening any faster than getting my iPod to work in VirtualBox.
This one defect aside, I absolutely love VirtualBox and will gladly use it until the cows come home. I just hope they can fix this issue somewhere in the forseeable future.