Just in case anyone viewing this thread is having similar problems, here are some more interesting bits:
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00:01:49.556 TM: Giving up catch-up attempt at a 62 112 917 339 ns lag; new total: 62 112 917 339 ns
00:02:04.309 Guest Log: VBOXNP: DLL loaded.
00:09:05.166 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.171 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.181 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.189 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.201 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.206 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.210 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:05.227 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:09:54.927 TM: Giving up catch-up attempt at a 60 641 015 427 ns lag; new total: 122 753 932 766 ns
00:10:12.205 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.224 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.233 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.242 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.583 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.614 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.640 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.651 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.664 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.699 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.742 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.863 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:10:12.971 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:13:06.147 Guest Log: VBOXNP: DLL loaded.
00:16:17.204 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.210 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.227 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.245 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.268 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.306 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.337 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.366 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.406 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.446 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.485 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.510 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.517 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.542 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.555 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.593 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.630 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.654 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.666 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.680 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.691 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.702 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.712 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.721 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.744 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.757 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.792 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.824 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:17.862 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.033 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.044 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.054 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.061 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.067 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.077 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.086 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.093 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.101 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.106 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.117 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.125 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.131 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.141 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.149 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.157 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.164 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.169 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.182 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.192 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.198 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.205 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.336 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.341 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.348 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.357 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.365 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.369 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.383 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.393 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.401 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.405 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.409 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.422 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.431 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.436 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.444 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.451 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.462 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:16:19.470 ERROR [COM]: aRC=VBOX_E_IPRT_ERROR (0x80bb0005) aIID={fd443ec1-0006-4f5b-9282-d72760a66916} aComponent={Mouse} aText={Could not send the mouse event to the virtual mouse (VERR_PDM_NO_QUEUE_ITEMS)} aWarning=false, preserve=false
00:20:25.215 TM: Giving up catch-up attempt at a 60 268 007 144 ns lag; new total: 183 021 939 910 ns
00:20:57.244 Guest Log: VBOXNP: DLL unloaded.
00:32:24.768 TM: Giving up catch-up attempt at a 60 069 192 318 ns lag; new total: 243 091 132 228 ns
00:42:56.386 TM: Giving up catch-up attempt at a 61 617 716 147 ns lag; new total: 304 708 848 375 ns
00:50:41.820 TM: Giving up catch-up attempt at a 60 433 501 268 ns lag; new total: 365 142 349 643 ns
01:00:57.003 TM: Giving up catch-up attempt at a 60 183 324 550 ns lag; new total: 425 325 674 193 ns
01:13:27.328 TM: Giving up catch-up attempt at a 60 309 303 431 ns lag; new total: 485 634 977 624 ns
I also found this thread describing similar issues specific to Virtualbox on Mac hardware, probably related to ACPI:
. I am running on a Macbook Pro 3,1.