[Solved] Get an error "Could not save the settings file"

[A.Delcroix]

I upgraded VBox to 3.0.4 on a Vista 64 host (French).
Since then, when trying to create a new virtual disk or deleting an existing one, I get the message "Could not save the settings file 'C:\Users\ddministrator\.VirtualBox\VirutalBox.xml' (VERR_ACCESS_DENIED)"
I am logged as administrator and activated the administrator rights on the host
When I try to edit and save that file with an editor, it says it is in use by another process, even when no Virtual Machine is executing

[vbox4me2]

While VBox is active it will remain in use. Other users usually don't have access rights to the xml files under administrator.

[A.Delcroix]

Thanks for your quick answer.
However, I do not fully understand what you mean.
I stopped all instance of VirtualBox (Task manager does not show any one running) and I still cannot create a new Virtual Disk

[vbox4me2]

Login as administrator and try again.

[Sasquatch]

If you still get the same error, use Process Explorer to discover which process is holding the file. A reboot is advised first, that will certainly close all handles to the file.

[A.Delcroix]

OK. Thanks... A reboot solved the problem. Maybe the upgrade process should terminate by saying "Must reboot the machine"
Thanks again for your help to everyone