virtualbox fails to open a session for the virtual machine

[serpentking]

I am attempting to open a virtual machine but I get an error that it is inaccessible.
How can I resolve this? Thanks!
Here is the copy of the error:

Failed to open a session for the virtual machine OS161-Bodhi.

Could not open the medium 'C:\Users\David\Desktop\OS161-Bodhi\OS161-Bodhi.vmdk'.

VD: error VERR_FILE_NOT_FOUND opening image file 'C:\Users\David\Desktop\OS161-Bodhi\OS161-Bodhi.vmdk' (VERR_FILE_NOT_FOUND).

Result Code: E_FAIL (0x80004005)
Component: MediumWrap
Interface: IMedium {ad47ad09-787b-44ab-b343-a082a3f2dfb1}