The guests are Windows 10 pro, Windows 7 Pro, Ultimate, and Pro N.
The Host machine has a Asus xonar dsx audio device and here is the systeminfo on it.
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OS Name: Microsoft Windows 10 Pro
OS Version: 10.0.15063 N/A Build 15063
OS Manufacturer: Microsoft Corporation
OS Configuration: Standalone Workstation
OS Build Type: Multiprocessor Free
Original Install Date: 2017-07-05, 10:48:34 AM
System Boot Time: 2017-09-06, 10:59:37 AM
System Manufacturer: Supermicro
System Model: SYS-7048R-TR
System Type: x64-based PC
Processor(s): 2 Processor(s) Installed.
[01]: Intel64 Family 6 Model 79 Stepping 1 GenuineIntel ~2201 Mhz
[02]: Intel64 Family 6 Model 79 Stepping 1 GenuineIntel ~2201 Mhz
BIOS Version: American Megatrends Inc. 2.0, 2015-12-28
Windows Directory: C:\WINDOWS
System Directory: C:\WINDOWS\system32
Boot Device: \Device\HarddiskVolume4
System Locale: en-ca;English (Canada)
Input Locale: en-us;English (United States)
Time Zone: (UTC-06:00) Central Time (US & Canada)
Total Physical Memory: 65,428 MB
Available Physical Memory: 56,272 MB
Virtual Memory: Max Size: 75,156 MB
Virtual Memory: Available: 65,613 MB
Virtual Memory: In Use: 9,543 MB
Page File Location(s): C:\pagefile.sys
Hotfix(s): 3 Hotfix(s) Installed.
[01]: KB4022405
[02]: KB4034662
[03]: KB4022725
Network Card(s): 3 NIC(s) Installed.
[01]: VirtualBox Host-Only Ethernet Adapter
Connection Name: VirtualBox Host-Only Network
DHCP Enabled: No
IP address(es)
[01]: 192.168.56.1
[02]: fe80::2cf4:f9c2:3b64:675b
[02]: Intel(R) I350 Gigabit Network Connection
Connection Name: OnBoard LAN 1
DHCP Enabled: Yes
DHCP Server: 10.0.0.75
IP address(es)
[01]: 10.0.0.116
[02]: fe80::2d6b:92c2:2cc0:583d
[03]: Intel(R) I350 Gigabit Network Connection
Connection Name: OnBoard LAN 2
Status: Media disconnected
Hyper-V Requirements: VM Monitor Mode Extensions: Yes
Virtualization Enabled In Firmware: Yes
Second Level Address Translation: Yes
Data Execution Prevention Available: Yes