Error -610 When Trying to Run VBox on Fedora 25

[sqlt]

I've gone through the install process, and was able to get everything situated. Now, when i go to run vbox, I get the following issue:

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VirtualBox: Error -610 in supR3HardenedMainInitRuntime!
VirtualBox: dlopen("/usr/lib/virtualbox/VBoxRT.so",) failed: <NULL>

VirtualBox: Tip! It may help to reinstall VirtualBox.

I'm running Fedora 25

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uname -r:
4.10.15-200.fc25.x86_64

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VBoxManage -v
5.1.22r115126

I've downloaded/installed all dependencies. Any help you guys can provide as to why I'm not able to get this running would be welcome.

[Perryg]

Easiest way is to disable secureboot in the hosts BIOS. Otherwise you need to create a Fedora signing key.

[sqlt]

Thanks for the quick response. Secure boot is turned off in hosts BIOS. I'm assuming it's not going to matter if it's legacy or UEFI.

Is there anything specific I'll need to do when creating the Fedora signing key?