Rick,
This is a problem with your Windows installer, trying to find an old installation. I suggest you do a complete uninstall of whatever VirtualBox previous installs you have. I see that the error is referring to VirtualBox 4.2.2, that's quite an old one. Did you have that installed before?
Previously such problems meant that the user had to download the named package (4.2.2) and not run the installer, but extracting the files
(which includes the "VirtualBox-4.2.2-81494-MultiArch_amd64.msi") to a temp folder and point the installer to that file. So, download the old installer, and then run:
VirtualBox-4.2.2-81494-Win.exe -extract
For reference, here's the link to that installer:
http://download.virtualbox.org/virtualbox/4.2.2/VirtualBox-4.2.2-81494-Win.exe